Skin Graft Suture Device A suturing device with sewing machine-like action for rapid skin graft quilting using absorbable thread with bristles or tines. The prototype has been used to carry out challenging urinary reconstruction skin grafts in 30 seconds. Additional applications include plastic surgery for burn victims, hernia repair, and battlefield surgery. Patent Pending... Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare, Campus > Upstate Medical University
Proprietary Doxorubicin Formulation Increases Survival and Safety Over Free Doxorubicin and Doxil Doxorubicin (DOX) is a commonly used anticancer chemo drug, and its clinical use is associated with dose-limiting cardiotoxicity. It is used to treat a wide variety of cancers including leukemia, bone and Karposi sarcomas, multiple myeloma, and ovarian, breast, kidney, endometrial, liver and gastric cancers. Despite being a generic, the market for liposomal... Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Biomarker Diagnostic for Crohn's Disease Severity There are approximately 1.8 million people suffering from Crohn's disease in the US and Europe. A portion of these will require aggressive treatment, such as surgical resections and biologics. Upstate has identified a novel mutant fusion mRNA that allows easy and definitive identification of a subset of Crohn's Disease patients that is highly... Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University
6-Mer Peptide for Anti-Cancer Therapeutic Use A 6-mer peptide (Win6mer) has been designed which has potential as an anti-cancer therapeutic. The Win6mer disrupts MLL1 and SETd1A core complex assembly, but does not inhibit isolated SET domain activity. MLL I belongs to the SETI family of histone H3 lysine 4 (H3K4) methyltransferases, comprised of MLLl-4 and SETdlA/B. MLLl translocations are present... Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Safe Neurmonitoring Needle Electrode SUNY Upstate Medical University researchers have developed a safety feature to protect medical technicians from needle sticks during surgeries requiring neuromonitoring. The novel safety flap can be attached to bare needles or combined with safety chambers (into which needles are retracted after use). When interoperative neuromonitoring probes are placed... Category(s): Technology Classifications > Medical Devices, Technology Classifications > Biomedical Science and Engineering, Campus > Upstate Medical University
Affinity Purified, Polyclonal Anti-Erlin2 Antibody Anit-erlin2 is an affinity purified rabbit polyclonal antibody raised against amino acids 321-339 of rat erlin2; DKLGFGLEDEPLETATKDN). Erlin2 is a recently-characterized endoplasmic reticulum (ER) membrane protein that that forms a complex with erlin1 and has a putative role in the cellular process known as endoplasmic reticulum-associated degradation.... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Affinity Purified, Polyclonal Anti-Erlin1 Antibody Anti-erlin1 is an affinity purified rabbit polyclonal antibody raised against amino acids 332-346 of rat erlin1; EPSGESPIQNKENAG). Erlin1 is a newly-characterized endoplasmic reticulum (ER) membrane protein that forms a complex with erlin2 and has a putative role in a cellular process known as endoplasmic reticulum-associated degradation. Its official... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Affinity Purified, Polyclonal Anti-HRD1 Antibody Anti-HRD1 is an affinity purified rabbit polyclonal antibody raised against amino acids 606 - 616 of human HRD1; RLQKLESPVAH). HRD1 is a ubiquitin-protein ligase (a.k.a. an E3) located in the endoplasmic reticulum (ER) membrane with roles in catalyzing the ubiquitination of misfolded and aberrant ER proteins. HRD1 is also known as synoviolin (synovial... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Polyclonal Anti-Stk25 Antibody Anti-Stk25 is a polyclonal rabbit antibody raised against a fusion of glutathione-S transferase (GST) and a region of Stk25 (NM_021537, residues 306-354) with minimal homology to Mst3 (NM_145465) or Mst4 (NM_133729). According to the NCBI, Stk25 encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases.... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
ZetaGen Therapeutics, Inc. ZetaGen Therapeutics develops combination products for regenerative medicine and oncology applications. www.zetagen.com Category(s): Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines, Campus > Upstate Medical University

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