SHIP1 Inhibitors to Augment Blood Cell Production and Transplantation and Kill Cancer Cells SUNY Upstate Medical University researchers have developed a class of small molecule compounds that show promise for treating multiple myeloma and myelosuppression that occurs with many cancer treatments. These drugs inhibit a gene called SHIP1 — a novel target in cancer treatment — and have been shown to kill cancer cells in the lab and extend... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Therapeutics and Vaccines
Affinity Purified, Polyclonal Anti-Erlin2 Antibody Anit-erlin2 is an affinity purified rabbit polyclonal antibody raised against amino acids 321-339 of rat erlin2; DKLGFGLEDEPLETATKDN). Erlin2 is a recently-characterized endoplasmic reticulum (ER) membrane protein that that forms a complex with erlin1 and has a putative role in the cellular process known as endoplasmic reticulum-associated degradation.... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Affinity Purified, Polyclonal Anti-Erlin1 Antibody Anti-erlin1 is an affinity purified rabbit polyclonal antibody raised against amino acids 332-346 of rat erlin1; EPSGESPIQNKENAG). Erlin1 is a newly-characterized endoplasmic reticulum (ER) membrane protein that forms a complex with erlin2 and has a putative role in a cellular process known as endoplasmic reticulum-associated degradation. Its official... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Affinity Purified, Polyclonal Anti-HRD1 Antibody Anti-HRD1 is an affinity purified rabbit polyclonal antibody raised against amino acids 606 - 616 of human HRD1; RLQKLESPVAH). HRD1 is a ubiquitin-protein ligase (a.k.a. an E3) located in the endoplasmic reticulum (ER) membrane with roles in catalyzing the ubiquitination of misfolded and aberrant ER proteins. HRD1 is also known as synoviolin (synovial... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
Polyclonal Anti-Stk25 Antibody Anti-Stk25 is a polyclonal rabbit antibody raised against a fusion of glutathione-S transferase (GST) and a region of Stk25 (NM_021537, residues 306-354) with minimal homology to Mst3 (NM_145465) or Mst4 (NM_133729). According to the NCBI, Stk25 encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases.... Category(s): Technology Classifications > Biological Materials, Technology Classifications > Research Tools and Reagents, Campus > Upstate Medical University
MitoGenetics, LLC MitoGenetics has developed therapeutic solutions for diseases associated with mitochondrial dysfunction. We are seeing promising results for treatment of Alzheimer's Disease.www.mitogenetics.com Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Campus > SUNY Old Westbury
Codagenix, Inc. Codagenix, Inc., is developing live attenuated vaccines using a software-based genome design algorithm that relies on whole-genome synthesis and it is unlike previous vaccine platforms. The Codagenix approach re-codes the target pathogens' own genome to be translated slowly in host cells. This re-recoding results in vaccine strain that is highly attenuated,... Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Viral Vectors, Campus > Stony Brook University