Proprietary Doxorubicin Formulation Increases Survival and Safety Over Free Doxorubicin and Doxil Doxorubicin (DOX) is a commonly used anticancer chemo drug, and its clinical use is associated with dose-limiting cardiotoxicity. It is used to treat a wide variety of cancers including leukemia, bone and Karposi sarcomas, multiple myeloma, and ovarian, breast, kidney, endometrial, liver and gastric cancers. Despite being a generic, the market for liposomal... Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Rationally Designed Aromatase Inhibitors as Anti-Breast Cancer Agents We have developed exemestane-based vinyl diazo compounds that act as aromatase inhibitors to be used in the treatment of cancer, particularly breast and ovarian cancer. Exemestane is structurally related to androstenedione and acts as an irreversible, steroidal aromatase inactivator. Our aromatase inhibitors are based upon the steroid scaffold... Category(s): Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Delivery
Nanosphere Delivery System for the Treatment of Spinal Cord Injury SUNY Upstate Medical University researchers have developed a controlled-released treatment for delivering a nerve repair drug precisely to areas of damage. With traumatic spinal cord injury or the neurodegenerative disease multiple sclerosis, demyelination of nerve cells lead to loss of motor function. The compound chondroitinase (cABC) boosts the... Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology
Tonus Therapeutics Tonus Therapeutics has developed a drug to treat Duchenne Muscular Dystrophy which occurs in 1 in every 3500 boys. There is no cure for this disease and it is a progressive disease with a life span of about 25 years. Our drug will slow the degradation of the muscles to keep the boys walking longer. www.tonustherapeutics.com Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Campus > University at Buffalo
PeptiDream, Inc. PeptiDream is a biopharmaceutical company that employs its proprietary Peptide Discovery Platform System (PDPS) Technology, a revolutionary next-generation hit finding platform for new drugs. PeptiDream can identify hit candidates against almost any drug target rapidly, allowing for faster planning and decision making as to drug ability. www.p... Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Campus > University at Buffalo
Daedalus Innovations, LLC Daedalus Innovations, LLC offers a line of high pressure devices specific for NMR spectrosopy. These devices allow the study of biophysical phenomenon, such as a drug binding, that cannot be studied by other methods. www.daedalusinnovations.com Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Bioinformatics, Campus > University at Buffalo
Concarlo Holdings, LLC Concarlo Holdings, LLCM can dramatically increase drug efficacy and diagnostic evaluations for ER/PR+ HER2- patients. IpY, a cdk inhibitor, specifically addresses drug resistance issues. Concarlo believes that, as a cdk inhibitor, IpY will have efficacy in many difference cancers. www.concarlo.com Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Campus > SUNY Downstate Health Sciences University
CH3 Biosystems, LLC Saving time and money for drug discovery and development. www.ch3biosystems.com Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Biomedical Science and Engineering, Campus > University at Buffalo
Abcombi Biosciences, Inc. Abcombi Biosciences is a pre-clinical vaccine and therapeutic development company dedicated to delivering “smarter” vaccine and anti-infective solutions. Overview: Abcombi Biosciences is a pre-clinical vaccine and therapeutic development company dedicated to delivering “smarter” vaccine and anti-infective solutions. To... Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Delivery, Campus > University at Buffalo
Codagenix, Inc. Codagenix, Inc., is developing live attenuated vaccines using a software-based genome design algorithm that relies on whole-genome synthesis and it is unlike previous vaccine platforms. The Codagenix approach re-codes the target pathogens' own genome to be translated slowly in host cells. This re-recoding results in vaccine strain that is highly attenuated,... Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Viral Vectors, Campus > Stony Brook University