Skin Graft Suture Device A suturing device with sewing machine-like action for rapid skin graft quilting using absorbable thread with bristles or tines. The prototype has been used to carry out challenging urinary reconstruction skin grafts in 30 seconds. Additional applications include plastic surgery for burn victims, hernia repair, and battlefield surgery. Patent Pending... Category(s): Technology Classifications > Medical Devices, Technology Classifications > Healthcare, Campus > Upstate Medical University
Proprietary Doxorubicin Formulation Increases Survival and Safety Over Free Doxorubicin and Doxil Doxorubicin (DOX) is a commonly used anticancer chemo drug, and its clinical use is associated with dose-limiting cardiotoxicity. It is used to treat a wide variety of cancers including leukemia, bone and Karposi sarcomas, multiple myeloma, and ovarian, breast, kidney, endometrial, liver and gastric cancers. Despite being a generic, the market for liposomal... Category(s): Technology Classifications > Drug Delivery, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
Biomarker Diagnostic for Crohn's Disease Severity There are approximately 1.8 million people suffering from Crohn's disease in the US and Europe. A portion of these will require aggressive treatment, such as surgical resections and biologics. Upstate has identified a novel mutant fusion mRNA that allows easy and definitive identification of a subset of Crohn's Disease patients that is highly... Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Campus > Upstate Medical University
6-Mer Peptide for Anti-Cancer Therapeutic Use A 6-mer peptide (Win6mer) has been designed which has potential as an anti-cancer therapeutic. The Win6mer disrupts MLL1 and SETd1A core complex assembly, but does not inhibit isolated SET domain activity. MLL I belongs to the SETI family of histone H3 lysine 4 (H3K4) methyltransferases, comprised of MLLl-4 and SETdlA/B. MLLl translocations are present... Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Healthcare, Campus > Upstate Medical University
A constituent purified from plant Arctium Lappa L as a novel cancer therapeutic In the United States there were more than 1.5 million new diagnosed cancer cases, and approximately 577,000 cancer-related deaths in the U.S. in 2012, according to the American Cancer Society. The development and discovery of newer anticancer therapeutics are still urgently needed. For the past four decades, cancer treatments have commonly been derived... Category(s): Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Method and device for preserving and imaging specimens while retaining information on spatial orientation of specimen in respect to reference objects Current Problem Researchers at SUNY Upstate Medical University and the University of Rochester have collaborated to create a method and device for preserving and imaging lumpectomy specimens while retaining information on the spatial orientation of the specimen with respect to reference objects. Currently, during a lumpectomy surgery, surgeons... Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
Radiotherapy Treatment Data Auditor and Archiver Advances in technology have increased the level of sophistication in Radiotherapy. Modern radiotherapy requires transfer of patient data between a planning and storage computer and radiotherapy treatment machine. The occurrence and increasing probability of radiation overdose (or underdose), caused by errors in data transmission immediately prior... Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Computers, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
Rationally Designed Aromatase Inhibitors as Anti-Breast Cancer Agents We have developed exemestane-based vinyl diazo compounds that act as aromatase inhibitors to be used in the treatment of cancer, particularly breast and ovarian cancer. Exemestane is structurally related to androstenedione and acts as an irreversible, steroidal aromatase inactivator. Our aromatase inhibitors are based upon the steroid scaffold... Category(s): Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Drug Delivery
Enhancement of Near Infrared Fluorescence Using Milk for Visualization of Ureteral Anatomy During Pelvic Surgeries SUNY Upstate Medical University researchers have developed a simple, safe, and cost effective solution to be used in near infra-red tissue imaging. Researchers at SUNY Upstate Medical University have developed an improved fluorescent compound used tissue imaging. Typical imaging of renal tissue is conducted using a common fluorophore in medical... Category(s): Technology Classifications > Healthcare, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices
Near Infrared Flourescence as a Guide for Nephrostomy Access in Rats SUNY Upstate Medical University researchers have developed a simple, safe, and cost effective solution to be used in near infra-red tissue imaging. Researchers at SUNY Upstate Medical University have developed an improved fluorescent compound used tissue imaging. Typical imaging of renal tissue is conducted using a common fluorophore in medical... Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Medical Devices

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